Molecular Medicine of Rheumatoid Arthritis: From Molecular Path Physiology to Novel Therapeutics and Evidence-Based Practice
نویسندگان
چکیده
ACPA: Anti-Citrullinated Protein Antibody; ACR: American College of Rheumatology; APRIL: A Proliferation-Inducing Ligand; BAFFR: B Cell Activating Factor Receptor; BLyS: B-lymphocyte Stimulator; BTK: Bruton’s Tyrosine Kinase; CRP: C-Reactive Protein; DMARDs: Disease-Modifying Antirheumatic Drugs; ESR: Erythrocyte Sedimentation Rate; EULAR: European League Against Rheumatism; FDA: Food and Drug Administration; GMCSF: Granulocyte-Macrophage Colony Stimulating Factor; GWAS: Genome-Wide Association Study; HAQ-DI: Health Assessment Questionnaire-Disability Index; HLA: Human Leukocyte Antigen; HRQOL: Health-Related Quality Of Life; JNK: Janus Kinase; M-CSF: Macrophage Colony Stimulating Factor; MYX: Methotrexate; PI3K: Phosphatidylinositol 3-Kinase; RA: Rheumatoid arthritis; RANKL: Receptor Activator of NF-κB Ligand; RF: Rheumatoid Factor; ROS/RNS: Reactive Oxygen and Nitrogen Species; Syk: Spleen Tyrosine Kinase; TACI: Transmembrane Activator and Calcium-Modulator and Cyclophilin Ligand Interactor; TNF: Tumor Necrosis Factor
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